CV

Massive increases in the availability of informative social science data are making dramatic progress possible in analyzing, understanding, and addressing many major societal problems. Yet the same forces pose severe challenges to the scientific infrastructure supporting data sharing, data management, informatics, statistical methodology, and research ethics and policy, and these are collectively holding back progress. I address these changes and challenges and suggest what can be done.

We develop a computer-assisted method for the discovery of insightful conceptualizations, in the form of clusterings (i.e., partitions) of input objects. Each of the numerous fully automated methods of cluster analysis proposed in statistics, computer science, and biology optimize a different objective function. Almost all are well defined, but how to determine before the fact which one, if any, will partition a given set of objects in an "insightful" or "useful" way for a given user is unknown and difficult, if not logically impossible. We develop a metric space of partitions from all existing cluster analysis methods applied to a given data set (along with millions of other solutions we add based on combinations of existing clusterings), and enable a user to explore and interact with it, and quickly reveal or prompt useful or insightful conceptualizations. In addition, although uncommon in unsupervised learning problems, we offer and implement evaluation designs that make our computer-assisted approach vulnerable to being proven suboptimal in specific data types. We demonstrate that our approach facilitates more efficient and insightful discovery of useful information than either expert human coders or many existing fully automated methods.

We highlight common problems in the application of random treatment assignment in large scale program evaluation. Random assignment is the defining feature of modern experimental design. Yet, errors in design, implementation, and analysis often result in real world applications not benefiting from the advantages of randomization. The errors we highlight cover the control of variability, levels of randomization, size of treatment arms, and power to detect causal effects, as well as the many problems that commonly lead to post-treatment bias. We illustrate with an application to the Medicare Health Support evaluation, including recommendations for improving the design and analysis of this and other large scale randomized experiments.

Matching is an increasingly popular method of causal inference in observational data, but following methodological best practices has proven difficult for applied researchers. We address this problem by providing a simple graphical approach for choosing among the numerous possible matching solutions generated by three methods: the venerable ``Mahalanobis Distance Matching'' (MDM), the commonly used ``Propensity Score Matching'' (PSM), and a newer approach called ``Coarsened Exact Matching'' (CEM). In the process of using our approach, we also discover that PSM often approximates random matching, both in many real applications and in data simulated by the processes that fit PSM theory. Moreover, contrary to conventional wisdom, random matching is not benign: it (and thus PSM) can often degrade inferences relative to not matching at all. We find that MDM and CEM do not have this problem, and in practice CEM usually outperforms the other two approaches. However, with our comparative graphical approach and easy-to-follow procedures, focus can be on choosing a matching solution for a particular application, which is what may improve inferences, rather than the particular method used to generate it.

Social scientists typically devote considerable effort to reducing measurement error during data collection and then ignore the issue during data analysis. Although many statistical methods have been proposed for reducing measurement error-induced biases, few have been widely used because of implausible assumptions, high levels of model dependence, difficult computation, or inapplicability with multiple mismeasured variables. We develop an easy-to-use alternative that generalizes the popular multiple imputation (MI) framework by treating missing data problems as a special case of extreme measurement error and correcting for both. Like MI, the proposed "multiple overimputation" (MO) framework is a simple two-step procedure. First, multiple (≈5) completed copies of the data set are created where cells measured without error are held constant, those missing are imputed from the distribution of predicted values, and cells (or entire variables) with measurement error are "overimputed," that is imputed from a predictive distribution with observation-level priors defined by the mismeasured values and available external information, if any. In the second step, analysts can then run whatever statistical method they would have run on each of the overimputed data sets as if there had been no missingness or measurement error; the results are then combined via a simple procedure. We also (will) offer open source software that implements all the methods described herein.

When respondents use the ordinal response categories of standard survey questions in different ways, the validity of analyses based on the resulting data can be biased. Anchoring vignettes is a survey design technique intended to correct for some of these problems. The anchors package in R includes methods for evaluating and choosing anchoring vignettes, and for analyzing the resulting data.

We introduce a new "Monotonic Imbalance Bounding" (MIB) class of matching methods for causal inference with a surprisingly large number of attractive statistical properties. MIB generalizes and extends in several new directions the only existing class, "Equal Percent Bias Reducing" (EPBR), which is designed to satisfy weaker properties and only in expectation. We also offer strategies to obtain specific members of the MIB class, and analyze in more detail a member of this class, called Coarsened Exact Matching, whose properties we analyze from this new perspective. We offer a variety of analytical results and numerical simulations that demonstrate how members of the MIB class can dramatically improve inferences relative to EPBR-based matching methods.

Population mortality forecasts are widely used for allocating public health expenditures, setting research priorities, and evaluating the viability of public pensions, private pensions, and health care financing systems. In part because existing methods seem to forecast worse when based on more information, most forecasts are still based on simple linear extrapolations that ignore known biological risk factors and other prior information. We adapt a Bayesian hierarchical forecasting model capable of including more known health and demographic information than has previously been possible. This leads to the first age- and sex-specific forecasts of American mortality that simultaneously incorporate, in a formal statistical model, the effects of the recent rapid increase in obesity, the steady decline in tobacco consumption, and the well known patterns of smooth mortality age profiles and time trends. Formally including new information in forecasts can matter a great deal. For example, we estimate an increase in male life expectancy at birth from 76.2 years in 2010 to 79.9 years in 2030, which is 1.8 years greater than the U.S. Social Security Administration projection and 1.5 years more than U.S. Census projection. For females, we estimate more modest gains in life expectancy at birth over the next twenty years from 80.5 years to 81.9 years, which is virtually identical to the Social Security Administration projection and 2.0 years less than U.S. Census projections. We show that these patterns are also likely to greatly affect the aging American population structure. We offer an easy-to-use approach so that researchers can include other sources of information and potentially improve on our forecasts too.

We discuss a method for improving causal inferences called "Coarsened Exact Matching'' (CEM), and the new "Monotonic Imbalance Bounding'' (MIB) class of matching methods from which CEM is derived. We summarize what is known about CEM and MIB, derive and illustrate several new desirable statistical properties of CEM, and then propose a variety of useful extensions. We show that CEM possesses a wide range of desirable statistical properties not available in most other matching methods, but is at the same time exceptionally easy to comprehend and use. We focus on the connection between theoretical properties and practical applications. We also make available easy-to-use open source software for R and Stata which implement all our suggestions. Political Analysis version An Explanation of CEM Weights

Background: Verbal autopsy analyses are widely used for estimating cause-specific mortality rates (CSMR) in the vast majority of the world without high quality medical death registration. Verbal autopsies -- survey interviews with the caretakers of imminent decedents -- stand in for medical examinations or physical autopsies, which are infeasible or culturally prohibited. Methods and Findings: We introduce methods, simulations, and interpretations that can improve the design of automated, data-derived estimates of CSMRs, building on a new approach by King and Lu (2008). Our results generate advice for choosing symptom questions and sample sizes that is easier to satisfy than existing practices. For example, most prior effort has been devoted to searching for symptoms with high sensitivity and specificity, which has rarely if ever succeeded with multiple causes of death. In contrast, our approach makes this search irrelevant because it can produce unbiased estimates even with symptoms that have very low sensitivity and specificity. In addition, the new method is optimized for survey questions caretakers can easily answer rather than questions physicians would ask themselves. We also offer an automated method of weeding out biased symptom questions and advice on how to choose the number of causes of death, symptom questions to ask, and observations to collect, among others. Conclusions: With the advice offered here, researchers should be able to design verbal autopsy surveys and conduct analyses with greatly reduced statistical biases and research costs.

We introduce a new framework for forecasting age-sex-country-cause-specific mortality rates that incorporates considerably more information, and thus has the potential to forecast much better, than any existing approach. Mortality forecasts are used in a wide variety of academic fields, and for global and national health policy making, medical and pharmaceutical research, and social security and retirement planning. As it turns out, the tools we developed in pursuit of this goal also have broader statistical implications, in addition to their use for forecasting mortality or other variables with similar statistical properties. First, our methods make it possible to include different explanatory variables in a time series regression for each cross-section, while still borrowing strength from one regression to improve the estimation of all. Second, we show that many existing Bayesian (hierarchical and spatial) models with explanatory variables use prior densities that incorrectly formalize prior knowledge. Many demographers and public health researchers have fortuitously avoided this problem so prevalent in other fields by using prior knowledge only as an ex post check on empirical results, but this approach excludes considerable information from their models. We show how to incorporate this demographic knowledge into a model in a statistically appropriate way. Finally, we develop a set of tools useful for developing models with Bayesian priors in the presence of partial prior ignorance. This approach also provides many of the attractive features claimed by the empirical Bayes approach, but fully within the standard Bayesian theory of inference.

Ecological Inference: New Methodological Strategies brings together a diverse group of scholars to survey the latest strategies for solving ecological inference problems in various fields. The last half decade has witnessed an explosion of research in ecological inference – the attempt to infer individual behavior from aggregate data. The uncertainties and the information lost in aggregation make ecological inference one of the most difficult areas of statistical inference, but such inferences are required in many academic fields, as well as by legislatures and the courts in redistricting, by businesses in marketing research, and by governments in policy analysis.

This program will read and analyze a large set of text documents and report on the proportion of documents in each of a set of given categories.

A program for analyzing most any feature of district-level legislative elections data, including prediction, evaluating redistricting plans, estimating counterfactual hypotheses (such as what would happen if a term-limitation amendment were imposed). This implements statistical procedures described in a series of journal articles and has been used during redistricting in many states by judges, partisans, governments, private citizens, and many others. The earlier version was winner of the APSA Research Software Award.

This program multiply imputes missing data in cross-sectional, time series, and time series cross-sectional data sets. It includes a Windows version (no knowledge of R required), and a version that works with R either from the command line or via a GUI.

YourCast is (open source and free) software that makes forecasts by running sets of linear regressions together in a variety of sophisticated ways. YourCast avoids the bias that results when stacking datasets from separate cross-sections and assuming constant parameters, and the inefficiency that results from running independent regressions in each cross-section.

This is a set of easy-to-use Stata macros that implement the techniques described in Gary King, Michael Tomz, and Jason Wittenberg's "Making the Most of Statistical Analyses: Improving Interpretation and Presentation". To install Clarify, type "net from http://gking.harvard.edu/clarify" at the Stata command line. The documentation [ HTML | PDF ] explains how to do this. We also provide a zip archive for users who want to install Clarify on a computer that is not connected to the internet. Winner of the Okidata Best Research Software Award. Also try -ssc install qsim- to install a wrapper, donated by Fred Wolfe, to automate Clarify's simulation of dummy variables.